As a general note, you have way too many capsules in there. Theres a hard limit for cloth to respond to those anyway so it likely just ignores the whole asset.
As far as a possible bug goes,
Try to make sure you are building for the final release and not for debugging or anything like that.
Instead of testing standalone launch the final exe manually to test.
Aside from that, it could have to do with bones being culled from metahuman out of beta/demo.
If so, That’s what you get for using epic’s trash in your projects folks! 
If that ends up being the cause, you can probably bypass the issue or at least get the same result in pie by setting up a single LOD with expressly set up bones. Assuming its the main character it will never LOD anyway.
Other possible things to look at…
- missing masterpose component linkage (node was renamed).
- Wrong cloth settings for simulation.
- Different PHAT on cloth definition.
- Colliding objects attached to character or present in base pose.