Changing character mesh at runtime breaks IK retargeting

I’ve got a few meshes sharing the same skeleton, which I’m dynamically retargeting to the mannequin. This works fine, but I tried to randomly select one of the meshes from an array at runtime, and they show up stuck in t-pose.

Is this a limitation of dynamic retargeting? As far as I can tell no settings except the mesh are being changed, and if I take out this logic and just change the meshes manually, they work fine. Thx!

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