Is it possible?
Yes and no.
If you were hoping to use vector based designs, components or animations then no, these are not transferable / compatible.
UE4 has its own UI editor - UMG, where reusable elements (widgets) - buttons, borders, lists, text blocks (and many more) form the actual user interface. You prettify the barebones widgets, animate them, use materials for more advanced UI effect and drive it all with blueprint script and/or code.
UMG does not really have tools for artistic expression per se so you must rely on an external application. Once you’re happy with the assets created in Adobe, you can import them as simple images. But you will need to reassemble the whole thing within the UMG framework.
Hoping for UE5 to bring a vector based UI tools suite. 
On the the other hand, if you’re versed in a Photoshop-like tool, it’s probably impossible to beat anyway.
I really understand thank you!!