I used UE4 this year with my Software Development Level 3 students to teach the games programming part of the course, with really good results.
Next year I may have a blind student on the course and I am trying to work out how I can include him in this unit.
The course specification needs him to code a working game with an example of iteration and selection, which should be possible using Blueprints.
My assumption currently is that his one to one will be able to describe the environment and follow his directions to build a Blueprint, possibly using audio, rather than visual assets.
I would be very interested if you have come across this before and if you have any resources I could use to help the student succeed.