It can, but it is something you need to work a bit with in order to get just right.
If you were working with the unreal mannequin I would suggest using my plug-in. You can try it either way - in fact, maybe you can utilize the skeleton by re-weight-painting your rig on the unreal bones.
I’s a lot of work just to get a mesh replaced, so I wouldn’t recommend it unless you know for a fact the bone hierarchy is the issue and you have no idea on how to make the bone structure on your own.