Animation seems to only work perfectly when debugging control rig but slightly off otherwise

I have a control rig with various IK setups running inside.

I noticed the IK in my character is subtly misaligned in game for unexplainable reasons. Then I open the control rig to debug it, attach it to my character, and I visibly see parts of my character snap into place where they should be. After that, closing the control rig tab leaves the character running perfectly.

Wondering if anyone else saw this? I’d file a bug report but my setup is very complicated.