Animating a Metahuman in Sequencer for use in a Game

Sounds like a retargeting issue. Unreal makes the whole retargeting process for Metahumans much more difficult than it should be. If you haven’t see the right setup for the root and pelvis(?0 there are issues. And if you don’t assign the right ‘body’ then there are issues>
The hunched shoulders was/is an issue in UE5. Are you using UE4.26.2 or UE55?