WPO is a very expensive material calculation, as it is asking the engine to dynamically distort geometry according to a material parameter. If you need to use it for a scene, then I would merge and minimize the number of instances using it, only have it enabled on the parts you absolutely need, and keep the parts in question as geometrically simple as possible. These rules are slightly different for Nanite, but given that Nanite with WPO is largely experimental, I’d stay away from using them if you’re shipping anytime soon.
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