Yes, you can. It’s all dynamic. Luckily, YT is choke full of spline tutorials.
One note, since you’ve yet to dive into UE4’s splines, when the coordinates of spline points are updated, the mesh that represents a spline segment (via a Spline Mesh Component) does not follow and update automatically.
If you alter the spline, you need to adjust the meshes. This is generally a non-issue unless you decide to do it every frame for 100s of cars. It’s not exactly cheap under those circumstances.