@Rareden
Make sure that Paragon skeleton has no sockets with names equal to bones (for example, sockets like foot_r and foot_l can break VRIKSkeletalMeshTranslator). I know that at least some Paragon characters have such sockets.
In general, update happens in VRIKBody::CalculateFrame and VRIKSkeletalMeshTranslator::UpdateSkeleton. You can call them before or after physics if you changed Ticking group in you blueprint (that’s why they’re called manually). If needed, you can even create dedicated blueprint actor with changed ticking group to call these functions.