I have not yet experienced an instance where I maxed out the available character limit in a Path variable, so I haven’t been in this situation before. It certainly makes sense to replace portions of paths that appear repeatedly in the Path variable with shorter variable names. I generally try to avoid messing with environment variables unless I have no choice, but I think if I were going to try this to see if it will help, I would prefer to do it myself instead of having it done automatically by someone else’s program.
Unfortunately I was not able to find a “safe” way to test the theory that the problem is in the Path file being at its character limit. I wanted to find a way to temporarily artificially fill up the variable without causing any other problems to occur, and I didn’t really feel comfortable with any of the options that I came up with. I suppose one good thing that came out of this is that I now have a concrete reason for telling people that they should remove duplicate paths from their Path variable.