It seems like a bug at this point if most user influenced decisions can’t really change the situation. Perhaps the combination of hardware is causing a glitch of some sort.
Could some other program be interfering with unreal in any way? A real-time virus scan / windows defender blocking access mid calculations to files?
Is your power plan set to adaptive or high performance? Maybe setting the gpu to not go into power saving might help. (sometimes the ramp up time can cause errors in programs)