https://www.reddit.com/r/Fedora/comments/w4v3pl/unreal_engine_5_on_fedora/?utm_source=share&utm_medium=web3x&utm_name=web3xcss&utm_term=1&utm_content=share_button is a significant step forward:
For those who haven’t heard the news this week Epic Games have made a Linux binary for Unreal Engine 5. Some useful Tools and Learning Resources for Unreal Engine 5. Also here are the Linux requirements for Unreal Engine 5. It’s say Ubuntu 22.04 but it has been tested and works fine on Fedora as well.