You should react to the pickups being hit, not Pacman as you’re probably going to have a lot more pickups in the level than 2. You can have several OnActorHit events in the Blueprint as long as they refer to different actors. Of course, you’ll need to check if the other actor hitting the pickup is Pacman rather than a ghost, but you’ll need to do that anyway.
Personally, I’d recommend moving the pickups into Blueprints of their own and to handle what happens when you pick them up (destruction and score increase) in their Blueprint.
Here’s a tutorial that explains how to build a Pickup item: Unreal Engine 4 Tutorial - Basic Pickup with Movement - YouTube