How can I tell my blueprint to react in a particular way when my cursor is located within a specific part of the screen?

[AceD]

Thank you! This was really helpful and it’s working with a few changes. I had to set the Mouse Position as the input instead of the Viewport Size.
The Mouse position increases from left to the right and with the ViewportSize as the input, i strangely couldn’t get the Middle Gun to work.
But it’s working now, thanks again!!