For other people who find this forum post, I forked a basic C++ class that did this then added support for more different kinds of parameters to adjust + material layer blend parameters as well. I also created documentation hosted online and under Releases you can find builds for UE versions from 5.1 to 5.5. GitHub - EJaworenko/UEAdvancedMaterialEditingLibrary: An Unreal Engine 5 plugin that enables programmatic editing of material layers and blend parameters through both Python and Blueprint interfaces.