Frame Time significantly exceeds the weight of other values such as Game, Draw RHIT, GPUTime

I see a lot of Oodle stuff going on here ( texture encoding ).

Are you using the latest engine? I recall there was an issue ( recently ) where Oodle had some sort of cache handling bug. It caused spikes like this.

You can try upgrading ( if need be ), or turn off Oodle ( plugins ).

Otherwise, I’d recommend this, particularly the asset tagging which help you find the culprit