The problem I was having in a setup very similar to @Ian_Dallas was that the transform I was setting from the Animation Blueprint did not match what I was seeing in the Control Rig. The way I solved this is by setting the Offset of controls to 0 and instead set their Initial transforms. Usually when rigging I use the Set Offset From Closest Bone functionality, the problem with this is that that offset is applied to whatever you set from your Animation Blueprint. There doesn’t seem to be a menu item for this, but there is a shortcut you can bind to Set Initial Transform From Closest Bone (Editor Preferences → Keyboard Shortcuts → Rig Hierarchy )
Figured this out by drawing a debug box of the transform inside the AnimBP (looked correct) and went into Play mode, then while still in play mode opened up the Control Rig window and switched from Editor Preview to the control rig running in game (dropdown right next to the Auto Compile button), which showed that my controls were way off.