Hey guys,
It just happened to me in 4.18.3 - but because i have “Run as admin” checked on the UE4Editor.exe (for obscure reasons) and i tried to “double click” on .uproject file from Total commander that was not running as admin - i.e. it tried to run applicaiton as admin without having access… So when i rerun total commander as admin then it worked fine without deleting any cached files or whatever
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