about the simplification levels. and detail settings.
I did quite a bit of testing. but each case will be different.
I was shooting with dslr from heli. so i was quite far away, and needing all the resolution i could get.
I found i was getting better building edges and cleaner models after simplifying from a high detail model vs normal.
but i was also getting really long processing times, in the 1 - 3 week range.
but its going to be best to make sure all your alignment is working well before you try running it out on high detail. otherwise you can just end up wasting your time.