Does it matter what scale a game is created at?

I’m afraid it does matter about the scaling. Because The numbers are often OFF. As when I was transferring assets from one project to another. I found the scaling numbers were different in the other project because I had a smaller skybox I was transferring over into while the other project had a bigger skybox and it affected some of the location positions of the brushes because the two skyboxes were not the same size…