However, even deleting single textures/meshes/materials etc cause the editor to freeze and become unresponsive for about 10-15 minutes if your project has a large file size. Additional, after deletion finished the auto-save features kicks in, adding another minute where you cannot work.
This is a long standing issue, which is really impacting workflow since especially with large projects you aim to get rid of overhead, but cleanup process is so slow that you think twice before trying to delete stuff.
Also, deleting closes all open windows