Hey LampChops -
Typically no the Config files should not be causing a crash in and of themselves unless you have added a console variable. We can try also to delete the Derived Data Cache Folder from the project directory and see if you can open the project afterwards, it should take a while to open as the engine will have to do a small amount of recompiling.
Let me know and I will continue to research this issue -
Eric Ketchum