Blender Rigging and Animation

Another question for you. Should I be aligning all of the UE4 Mannequin Armature Skeleton Layers to my character? From my understanding layer 2 is the IK bones which are not required. But I’m confused about the other layers. The ones i’m talking about are in the UE4 Tools Mannequin.

Here is what I have right now. I’m a bit confused why if I leave the hand bones un-aligned with my character they seem to work better once imported into Unreal. I think I need to re-watch that Alien movie so I know what you’re talking about!