Hello ,
Your hardware is more than capable of using Path Tracer, so I don't believe this should be causing issues, but to be sure, it might be worth checking to see if you need to update your drivers, particularly for your GPU.
If the drivers are not the cause of the issue, then please submit a Bug Report and share your Twinmotion file with our support team so we can figure out what might be going wrong.
Best,
Raghib