Okay, this is something that takes a lot of practice and learning, and means you do not have a specific question Im going to have to recommend some tutorials by epic themselves, as I believe its one of the best places to get started learning. Because explaining how to setup a whole animation blueprint would take pages.
Start with these tutorials:
Character Animation in UE4 | Live Training | Unreal Engine Livestream - YouTube
These are tutorial series with multiple parts, you can find all of them on epics youtube channel.
I Hope that helps! 