The ISM tool is seriously amazing. I was able to take a level with a lot of scaled around meshes (cave made out of rocks) and quickly go through and turn them into ISMs - performance got a huge boost. It will also be super useful for hand editing the random-gen levels that the Turn Based Strategy Example spits out (I modified it so you can run it in editor to generate levels at design- and hand-edit them). Before I was having to figure out their coordinates and then find the instance that way, manually!
Thanks 
Edit: It would be awesome if you could make it so it was possible to select individual instances after an ISM is made and translate/scale/rotate them without converting back. But that’s just gravy.