I’m having the same issue with the vehicle destruction in City Sample vehicles. These use the control rig to deform, and I’m 99% sure now that it is the control rig not doing anything in standalone or even packaged. In fact, I did a fresh install of 5.0.1 on a different machine to the one I’m currently using, downloaded the City Sample there, and running that standalone behaves the same way. The control rig is only deforming the vehicle upon collision when it runs in the editor.
No solution, just that this seems like a bug.