Hi Eric,
It is a combination of Graphics card and output connections.
980 GTX with 2 Display, 1 DVI and 1 HDMI (All FullHD) = Ok.
980 GTX with 3 Display (of which 2 Full HD projectors and 1 Full HD Monitor) + Full HD projector on HDMI = Driver crash (347.52)
However, I have to let you know that 1 frame becomes visible, at that frame I do create 4 more Full HD render targets. So it may have to do with that. But the 980 has almost 4GB of available memory and I have not seen the threshold of 1.9 Gb been passed yet.
Furthermore, on a much lower end card a 780 GTX it does not crash with the same resolution setup, though the connections are different. Namely:
Out 2x DVI->HDMI In
Out 1x Display->HDMI in
Out 1x HDMI->HDMI in
This works fine.
However, I have noticed that resizing render targets at runtime will slow down the engine entirely and it will not catch up anymore. That is, if you create 5x512x512 render targets in the editor and use it on a a 5xSceneCaptuerer2D or you create 5x2048x2048 in editor and resize it to 5x512x512 at runtime, the performance is not the same after resizing, it will be slown down majorly!