So the problem probably was bad RAM from G.Skill, I have set it to 3000Mhz as it should be because I overpaid just to get this speed, I had to lower it to 2400Mhz which is significantly lower. Don’t blame Substance Painter when it asking to modify registry keys, it’s totally Okay, sorry I have blamed it. My restarts were happening anyways, so only changing BIOS settings to basic level probably helpmed me, I don’t know yet, I have to test it for week or more to get clear idea. If there no crashes, then it was bad RAM overlocking failures.