There’s currently no way to mark a sprite asset so that all components using it will default to being physically simulated. I’ll add it to list to consider. Creating a Blueprint that contains a sprite component and setting it on component there should be way to go, so I’m not sure why you can’t enable simulate on it. It certainly seems like a bug, although I’m seeing same behavior on both SpriteComponent and StaticMeshComponent: I cannot edit bSimulatePhysics on either in Blueprint Components mode. I’ll ask around to see if anyone else knows why.