Unfortunately not. The thing is that the Easetypes need a defined beginning and end to work properly since it’s taking two values, finding a point in between, then asking the equation how to modulate said value.
You can however start a tween then stop it and start another one if the end value changes. Use speed instead of time for this because speed accounts for distance whereas time will always finish in a defined number of seconds.
You can also move the goalposts for the tween by changing the end value directly after first setting it off, but this may not give you the results you want. It may rush or slow too much to fit within the time frame you want to maintain.