My mouse lift click does't work any more

I am at my wit’s end. I tried everything conceivable and I still can’t fix it. I am not able to use my left click on my mouse.
I have been trying for a week looking for an answer. If anyone has a fix or update PLEASE help. I tried switching my mouse 3 different times. I uninstalled the program and reinstalled, still didn’t work. I’ve read so so so many articles on how to fix this situation and nobody has a fix. Did I mistakenly hit something on my Keyboard?

Are you talking about the editor or the OS?