Making a vehicle interior a seperate map?

Definitely would do this with one vehicle. You can separate the meshes perhaps (very common), but it makes no sense to move them to another part of the level IMO, unless your proportions are all out of whack (and it’s only a single-player game).

Just attach the interior mesh to the exterior, hide the exterior when inside, hide the interior when outside. Render Targets are absurdly expensive, I would strongly advise against those.