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Jazz Jackrabbit 3D by Dean Dodrill not working on Windows 10

I tried enabling all system functions and installing dxwnd, but it didn’t solve the problem.

That game was never released… And was slated for release in 2000 if I’m correct. So there is no real support for that game.
That would not work in Win10. Also, do you really have this game? Or are you using the Alpha demo?

And the alpha demo only worked in win98se for me. But I only tried it in Windows ME… So it might work in XP or in a VM.

it worked in windows 7 at least