Publishing a game with the help of Quixel Bridge/Megascans can surely save you a lot of time, but before you do that, I advise you to read more about texture resolutions, polycounts, and most importantly artistical consistency.
If you want your game to be performant literally on a maximum of computers, then you may have to look for other options other than Quixel Bridge. You’ll want to have very low poly assets, you will still be able to have a beautiful game by maintaining good art direction, you can learn doing art by yourself or hire an artist.
Otherwise, if you want your game to be performant on the average pc and up, which according to Steam, last time I checked, is a pc running a GTX 1060 6GB; then you can use Quixel Bridge, but still make sure to not use a very high texture resolution just because it looks detailed up-close. The bigger an asset, the higher resolution its texture will need to be, but don’t go higher than 4K, if you can stay at a maximum of 2K, it will be great. As for the Quixel Bridge 3D models, make sure you only use those with an acceptable amount of polycount.
Hope this clears it up!