Destructible mesh and AMD?

I myself am using a Nvidia card, but I want to know if AMD users are going to be able to use destructible meshes, since they are going to be a big part of the game. I have heard it will run off of the cpu if it does not detect a Nvidia card, but I am not sure and would like to know before I start developing with destructible meshes.

Yeah, every physics related thing will use the CPU and AMD users will be fine.