I would love to study law on this. It seems it depends. Myself I decide who I do business with and offer my services to. I write my own agreements. I don’t do this on the EPIC marketplace (yet). This freedom of choosing who you do business with is normally ok. On the wiki a context is described in which this behavior is used to inflict damages, which should be described in the anti-trust laws.
Since 99.9% of sellers will not be lawyers such freedom will likely have to be decided by the marketplace itself.
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Edit: It’s strange when you think of it. If the marketplace offers full freedom and by some media influence a large group decides to stop doing business with a certain country, there is a problem because it will be noticable and this specific marketplace is affected. If it’s just one guy deciding the same thing (but not to inflict damages) then it’s fine. Sure there must be solutions to this. There is the option of setting up your own webshop, that is a very different road but it is a road.
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Edit 2: Or, sellers get full freedom. When you start a business you know you have to deal with laws and you know you need to dig a bit. You could say unless law states so, it’s not the marketplace who should instruct / deal with misbehaving sellers unless it wants to.