Now that UE4 is free, a lot of people have come to try and explore UE4. So, to prevent the making of many threads it would be a good idea for anyone who wants to ask a question do so as a comment on this thread and those who want to answer these questions can also look at this thread. This avoids unanswered questions from going to page 2+ where most people don’t look, and also a chance that someone else has asked your question comes up. If there are many people interested in this idea, I may take the questions from the comments and post it here in 2 parts : answered and unanswered so that people can easily find answers directly 
What are the best programs for making 2D Textures/Sprites/Animated Sprites