2.5D isometric Game

Hello Folks I’m new In this engine, I hope you can help me, I want to know if it is posible to develop a 2.5D isometric game with the paper tool or with a normal configuration of the engine, also I want to try to program all the game with the blue prints, it is posible ?, I had read a lot of documentation but has not specifications in that topics.

Thanks and sorry for my bad English.